Of the participants included in the study, five reported having comorbidities, including one case of type I diabetes mellitus and hypothyroidism (under use of insulin and levothyroxine (Levoxyl)), one case of dyslipidemia (without medication use), and two cases of depressive mood disorder taking psychoactive medications (sertraline, risperidone (Risperdal), and venlafaxine). Here, INS is linked to metabolic syndrome.