In cervical cancer, these mediators remodel the tumor microenvironment (TME) by orchestrating angiogenesis, epithelial-mesenchymal transition (EMT) [13, 14], and metastatic dissemination, where CXCR7 has demonstrated prognostic significance through CXCL12-mediated migration regulation [15]. The gene discussed is CXCL12; the disease is neoplasm.