PCSK9 and familial hyperaldosteronism: Globally, LDLR is the most common mutant gene causing monogenic FH in 80–85% of molecularly diagnosed patients, followed by APOB gene in almost 5% of the cases and each of the PCSK9, LDLRAP1, ABCG5 and ABCG8 is mutant in less than 1% of molecularly diagnosed patients [34].