The frequencies of basal keratinocytes (KC1 [KRT15]) and suprabasal keratinocytes (KC3 [KRT1 and KRT10]) were decreased in both neutrophilic dermatoses, whereas the frequencies of stratum granulosum keratinocytes (KC2 [KLK13)]) and interferon-activated keratinocytes (KC8 [IRF1, WARS, and CXCL10]) were increased in patients with SS and PG (see Fig E2, F). The gene discussed is IRF1; the disease is synovial sarcoma.