KL and Intervertebral disk degeneration: The reduced proliferation and increased senescence of nucleus pulposus cells (NPCs) are associated with the aging process of intervertebral discs (IVDs), consequently contributing to intervertebral disc degeneration (IVDD),1, 2, 3 and also defective expression of the anti‐aging protein Klotho (KL) is linked to various age‐related diseases, including IVDD.4, 5, 6, 7