CD4 and cancer: UCPVax is a therapeutic anti-cancer vaccine consisting of the telomerase-derived helper peptides UCP2 (TERT578–592:KSVWSKLQSIGIRQH) and UCP4 (TERT1041–1055: SLCYSILKAKNAGMS), designed to stimulate vigorous TH1 CD4 T cell responses in individuals diagnosed with cancer [105].