In DLB total cohort, higher CSF levels of SERPIN E1 were associated with a higher age at examination (r = 0.366, p = 0.002), a higher age at onset (r = 0.335 p = 0.006) and higher h-TAU levels in CSF (r = 0.341, p = 0.005). This evidence concerns the gene SERPINE1 and Lewy body dementia.