We observed a higher prevalence of blood-thinning medication intake, including inhibitors of platelet aggregation or anticoagulants, in PD patients with the highest levels of SERPIN E1 (lowest tertile: 10/139 (7.2%), mid tertile: 22/135 (16.3%), highest tertile: 35/138 (25.4%), p ≤ 0.001). Here, SERPINE1 is linked to Parkinson disease.