The role of IL-17 in atherosclerosis is complex and context dependent, with the potential to both promote atherosclerosis by increasing inflammation and improve atherosclerosis by promoting tissue repair roles.69 Interestingly, Il-17 has been shown to contribute to I/R injury by regulating cardiomyocyte apoptosis and neutrophil infiltration.70 We speculate that 1938 may protect against IL-17-mediated cardiotoxicity, but this will require experimental investigation. Here, IL17A is linked to atherosclerosis.