CD36 and pneumococcal infection: In the context of infection, CD36 can partner with TLR2 to bind to lipoteichoic acid to facilitate response to gram-positive pathogens, such as S. pneumoniae and S. aureus, where CD36 knockout mice are hypersusceptible to S. aureus infection (52, 53) and are immunosuppressive in response to pneumococcal infection (54).