Exclusion of LUMA from total tumor yielded the highest risk score, indicating that LUMA has the best prognosis, followed by HER2 and LUMB, whereas BASAL and NORMAL were assigned worse prognosis (Hennigs et al., 2016; Ahn et al., 2015; Yersal and Barutca, 2014; Figure 4e and f). Here, TMEM43 is linked to neoplasm.