The results showed that each tumor component shared <i>TP53</i> c.1015G>T (p.Glu339Ter), <i>ERBB3</i> c.889G>A (p.Asp297Asn), and <i>CDKN2A</i> c.416G>A (p.Gly139Asp) mutations, suggesting that the adenocarcinoma might have differentiated into NET G2.<h4>Conclusions</h4>In this case report, the tumors shared a common genetic mutation, suggesting that MiNENs with NET components may share a common origin. Here, TP53 is linked to neoplasm.