Furthermore, the conversion of endogenous LC3B-I to the lipidated form LC3B-II (LC3B-phosphatidylethanolamine) was accelerated in the ZrMOF, PD/ZrMOF, and DOX-hyd-PD/ZrMOF treatments, revealing an increase in the number of autophagosomes in the cancer cells (Fig. 6E). This evidence concerns the gene MAP1LC3B and cancer.