IgE-ELISAs with HDM allergy patients' sera showed that r-Na_K-ATPase β2, r-Prx1, and r-Prx2 had IgE-binding rates of 7.2% (9/125), 8.5% (12/143), and 6.7% (6/90), respectively (Fig. 2B); r-CFGA showed no IgE-binding (0%, 0/75) (Fig. S4). This evidence concerns the gene IGHE and allergic disease.