FGFR2 and craniosynostosis: Apert syndrome (AS) is a rare genetic condition caused by mutations in the fibroblast growth factor receptor 2 and characterized by craniosynostosis, midface hypoplasia, and complex syndactyly.1,2 Hallmark features include a long and narrow head, midface retrusion, and proptosis.1 Multisuture craniosynostosis is nearly universal, with bilateral coronal involvement affecting most patients and frequent sagittal and/or lambdoid involvement.3