Pts with advanced NSCLC;IBI318/LY3434172 mono;IO-failed NSCLC, N= 10; immunotherapy-naïve NSCLC pts with a PD-L1 TPS of 1–49%, N=8; treatment-naïve NSCLC pts with a PD-L1 TPS ≥ 50%, N=11;. The gene discussed is CD274; the disease is non-small cell lung carcinoma.