16 RRMS, 2 CIS vs 3 OND (Neurosarcoidosis, Atypical Neuroinflammatory Syndrome with uveitis and AQP4+ Neuromyelitis Optica) and 3 HCs (only 12 RRMS, 1 OND and 3 HCs were used for scRNA-seq). This evidence concerns the gene AQP4 and neurosarcoidosis.