Notably, 11 of these tumor types (CHOL, mesothelioma [MESO], uveal melanoma [UVM], PCPG, soft tissue sarcoma [STES], STAD, LAML, cervical squamous cell carcinoma [CESC], PRAD, HNSC, and BRCA) exhibited a significant positive correlation with ME1, while a significant negative correlation was observed in 3 tumor types (THCA, BLCA, and TGCT) (Figure 6C). Here, ME1 is linked to mesothelioma.