BIRC6 and colorectal cancer: BIRC6 is found abundantly in the brain, testis, bone marrow, lymphoid, and endocrine tissues [ 8] and plays a key role in the survival and patients’ prognosis as well as resistance/response to treatment in different types of cancers, such as lung cancers [ 9], ovarian cancers [ 10], colorectal cancers [ 11], and prostate cancers [ 12] and suggested as a novel biomarker for targeted anticancer therapy.