Considering the individual loadings on PC2 and PA, we found that patients who engaged in moderate PA had lower levels of CXCL9, CXCL10, and CXCL11, known pro-inflammatory chemokines involved in immune cell migration (Callahan et al., 2021; Elemam et al., 2022) and tumor progression (Chang et al., 2013; Liu et al., 2011; Wang et al., 2022). The gene discussed is CXCL11; the disease is neoplasm.