NHLRC2 and fibrosis, neurodegeneration, and cerebral angiomatosis: To study the pathophysiology of FINCA disease, we previously generated a mouse expressing the FINCA variant (NHLRC2 p.Asp148Tyr) in one allele and Nhlrc2 knockout (KO) in the other allele (FINCA mouse hereafter), similar to the genotype of first identified Finnish patients.