Univariable analyses demonstrated that APTT, TT, APTT/TT, tumor size, and LNMs were significantly correlated with DFS (HR:.1.104, 95%CI: 1.008-1.209, p=0.034; HR: 0.829, 95%CI: 0.714-0.961, p=0.013; HR: 7.626, 95%CI: 2.006-28.985, p=0.003; HR: 1.646, 95%CI: 1.115-2.430, p=0.012; HR: 2.520, 95%CI: 1.851-3.430, p<0.001), but there were no DFS differences in HCT, MCV, PLT, FIB, ER status, her-2, Ki-67 and other levels (Table 2). The gene discussed is MKI67; the disease is neoplasm.