Gene expression profiles of neuroblastoma patient tumors identified subsets of neuroblastoma tumors with FGFR1-4 overexpression, upwards of two standard deviations (z-score > 2) from the mean relative FGFR expression levels [Supplementary Figure 1], suggesting that subsets of neuroblastoma tumors are likely more sensitive to FGFR inhibition despite the relatively small percentage of tumors with gene alterations. The gene discussed is FGFR1; the disease is neuroblastoma.