FGFR4 and brain neoplasm: The rates of alterations of the FGFR1, FGFR2, FGFR3, and FGFR4 genes in brain tumor patient samples were 1%, 1.5%, 1.7%, and 0.9%, respectively [Figure 2A], and pediatric brain tumors had among the highest levels of FGFR gene family alterations among all brain tumor databases [Figure 2B].