Assessment using the top two TRA clones versus mutation VAF showed high correlation with RHOAG17V and IDH2R172 indicating the tumor specificity of these mutations, but was skewed with TET2 and DNMT3A mutations, suggesting their presence in progenitor cells in some AITLs (i.e., clonal hematopoiesis of indeterminate potential: CHIP) [38] (Figure S5G). The gene discussed is DNMT3A; the disease is neoplasm.