Blocking the CXCL10–CXCR3 axis effectively prevented T cell infiltration and neurodegeneration in AD cultures, identifying this chemokine as a potential therapeutic approach.[96] Other studies focused on unraveling the effects of tau proteins, commonly referred to as neurofibrillary tangles (NFTs), and their role in the progression of AD.[97, 98]. This evidence concerns the gene CXCR3 and Alzheimer disease.