This model is designed to study key features of AD, including Aβ aggregation, phosphorylated tau accumulation, and neuroinflammatory activity, aiming to provide a more precise human brain model for studying neural‐glial interactions and drug discovery in AD (Figure 2).[95] Furthermore, to study the molecular mechanisms underlying immune cell infiltration in AD, Jorfi et al. The gene discussed is MAPT; the disease is Alzheimer disease.