Upregulation of, for example, AURKA, AURKB, BIRC5, CCNA2, CCNB1, CDK2, CDC20, CDC25C, GTSE1, or MKI67 correlated with poor prognosis of PCa patients and more aggressive PCa [38, 39, 40, 41, 42, 43, 44, 45, 46]. Here, AURKA is linked to posterior cortical atrophy.