ITGAM and gastroenteritis: In addition, the Alg gel was used to encapsulate bifidobacterium (Bac) and drug-modified nanoscale dietary fibers (NDFs) through the electrostatic droplet generator to create hydrogel microspheres (NDF-Ms), which led to a significant reduction in CD11b+Ly6G+ neutrophils and CD11b+F4/80+ macrophages, resulting in a marked decrease in the inflammatory response of 5-ASA in NDF-M1/H at the site of intestinal inflammation [32].