The mouse models for NLRP3 inflammasome-associated inflammatory diseases used in our previous studies—including DSS-induced colitis [42], uric acid crystal-induced peritonitis [43], and IgA immune complex-induced IgA nephropathy [44]—can be employed in future research to further explore in vivo efficacy and safety. The gene discussed is NLRP3; the disease is IgA glomerulonephritis.