The control participants with dyspareunia had significantly lower levels of IL-8 and MCP-4 compared to the control participants without dyspareunia in the past 12 months (IL-8: GM for yes of 4.64 with 95% CI of 4.41–4.89 vs. GM for no of 4.99 with 95% CI of 4.82–5.17, p = 0.02; MCP-4: GM for yes of 57.7 with 95% CI of 50.7–65.6 vs. GM for no of 67.7 with 95% CI of 61.9–73.9, p = 0.05; Figure 2 and Figure 3; Table S3). This evidence concerns the gene CXCL8 and Dyspareunia.