CX3CL1 and myocardial infarction: Furthermore, when the therapeutic role of anti-CX3CL1 antibody administration was examined by inducing myocardial infarction in mice, survival and cardiac function were significantly improved in the group treated with anti-CX3CL1 antibody after myocardial infarction In vitro experiments also showed that CX3CL1 administration to cardiac fibroblasts enhanced fibroblast proliferation; CX3CL1 treatment in myocardial fibroblasts also enhanced fibroblast proliferation in in vitro experiments [90].