Such neoplasms involve platelet-derived growth factor receptors (PDGFR)A and PDGFRB, fibroblast growth factor receptor (FGFR)1, pericentriolar material 1 (PCM1)-JAK2, FMS-like tyrosine kinase 3 (FLT3), and tyrosine protein kinase v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1). The gene discussed is FLT3; the disease is neoplasm.