Moreover, the contradictory findings may be explained by the fact that increased AVP levels were found especially in ischemic stroke patients, and they were related to delayed neuronal damage following ischemic and reperfusion, meaning that AVP and copeptin levels may play a more significant role in the longitudinal view of stroke patients, rather than the transverse view, in a single assay, when the patient is at the emergency ward. This evidence concerns the gene AVP and stroke disorder.