However, in a later study from 2015, the authors reported a higher risk of BC in MLH1 PV carriers of up to 18.6% and only a 11.2% for MSH2 carriers, concluding that women with PVs in MLH1 and MSH2 genes should be considered for breast screening at earlier ages than those recommended by national screening programs [52]. Here, MSH2 is linked to breast cancer.