Interestingly, ΔI1023_V1024-CFTR has shown a response to Elexacaftor/Tezacaftor/Ivacaftor (ETI) in vitro [6], indicating a potential clinical benefit of ETI for people with CF (pwCF) who have ΔI1023_V1024-CFTR. This evidence concerns the gene CFTR and cystic fibrosis.