Additionally, treating neuroblastoma cells with MG149, a KAT8 inhibitor, impairs global H4K16 acetylation and autophagy regulator PTEN-Induced Kinase 1 (PINK1) expression of neuroblastoma cells further inhibiting autophagy receptor p62 recruitment, resulting in autophagy [86]. The gene discussed is KAT8; the disease is neuroblastoma.