In oesophageal squamous cell carcinoma (ESCC) cells, KAT8 catalyzed the acetylation of fascin actin-bundling protein 1 (FSCN1) at lysine 41, enhancing its F-actin-bundling activity and promoting filopodia/invadopodia formation to drive ESCC cell invasion [90]. This evidence concerns the gene FSCN1 and esophageal squamous cell carcinoma.