Additionally, KEGG pathway enrichment analysis was conducted on the 64 target genes, and the top 20 pathways were visualized using Cytoscape 3.9.0, represented as an octagon plot, as shown in Figure 3B. The analysis of these top 20 KEGG pathways revealed that the most enriched pathway was associated with psoriasis-related chemokine targets, including the chemokine signaling pathways and the PI3K-AKT signaling pathways (Table S5). Here, AKT1 is linked to psoriasis.