DARPins binding to such tumor-associated molecular targets, such as human epidermal growth factor receptor 2 (HER2), epithelial cell adhesion molecule (EpCAM), epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF), and hepatocyte growth factor (HGF) have been described [9,10,11,12]. This evidence concerns the gene EGFR and neoplasm.