AKT1 and diabetes mellitus: Figure 4b displays the top 30 signaling pathways that were enriched out of 167 KEGG pathway keywords that met p < 0.05. The results of the KEGG pathway enrichment analysis indicated that the molecular mechanism of Chaga in treating diabetes may involve the PI3K/Akt signaling pathway, Ras signaling pathway, RAP1 signaling pathway, MAPK signaling pathway, etc. The main signaling pathway directly involved in glucose metabolism-induced diabetes is the PI3K/Akt signaling pathway (Figure 4c).