MBOAT7 and metabolic dysfunction-associated steatotic liver disease: A disturbance in TLR signaling leads to tissue damage and a deficiency of MBOAT7 in macrophages, as observed in MASLD; this alters the membrane phospholipid composition in association with a redistribution of arachidonic acid toward proinflammatory eicosanoids, the induction of endoplasmic reticulum stress, and mitochondrial dysfunction [57].