Further studies on clinical samples of CRC include Kumagae et al. who analyzed the levels of MTH1 protein in 56 tissue samples of formalin-fixed and paraffin-embedded CRC (14 cases), dysplasia (9 cases), ulcerative colitis without neoplasm (16 cases), and healthy colon specimens (17 cases). The gene discussed is NUDT1; the disease is neoplasm.