Figure 1 depicts the COO classification determined by the GEP and genetic classification of DLBCL samples into groups EZB, MCD, BN2, and N1 based on alterations in EZH2, BCL2, MYD88, CD79B, BCL6, NOTCH2, and NOTCH1. This evidence concerns the gene BCL6 and diffuse large B-cell lymphoma.