MEN1 and pancreatic insulinoma: The miR-24-3p was selected for the present study, since previous studies revealed the existence of a direct negative feedback loop between the miR-24-3p, MEN1 mRNA, and menin protein, both in parathyroid tumor tissues from MEN1 patients and in endocrine pancreas-derived cell lines (the MIN6 mouse insulinoma cells, the βlox5 immortalized human pancreatic beta cells, and the BON1 human cell line derived from a lymph node metastasis of a pancreas neuroendocrine tumor) [15,16,30,31].