Of note, we also included the evaluation of three asymptomatic ATXN7 mutation carriers and, while these numbers are too low to establish meaningful outcomes, we observed a similar trend of higher GFAP in the CSF of asymptomatic SCA7 (148,801 pg/mL) compared to the controls (8906 pg/mL; Figure 1A and Table 1). Here, ATXN7 is linked to spinocerebellar ataxia 7.