TNF and bacterial infectious disease with sepsis: The baseline levels of all parameters were similar between cGAS−/− and WT, while sepsis induced higher levels of all parameters compared to the baseline, except for serum creatinine (Figure 1B), including liver enzymes (Figure 1C,D), cells in the complete blood count (CBC) (Figure 1E–G), bacteremia (Figure 1H), endotoxemia (Figure 1I), cell-free DNA (Figure 1J), and serum cytokines (TNF-α, IL-6, and IL-10) (Figure 1K–M).