Another striking result was that tumor presence was detected in 7 mice from a group of mice consisting of 19 one-year-old LPO gene-deleted mice; the tumors were various, including carcinoma within the lung; lymphoma adjacent or attached to the heart, mesentery, pancreas, salivary glands, or lung; in the spleen or small intestines; pleomorphic sarcoma in the skin; and histiocytic sarcoma in the spleen, liver, or bone marrow, while none of them were detected in the wild-type mice used in the study. The gene discussed is LPO; the disease is neoplasm.