SNCA and Parkinson disease: The role of mitochondrial energy metabolism, including production of adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD+), plays a critical role in the etiology and pathogenesis of PD [64,65,66], therefore optimizing a therapeutic option that enhances energy metabolism and may counteract alpha-synuclein aggregation and attenuate inflammation [67,68,69].