Since RAB4B-EGLN2 locus rs111833532 I/D, according to the allele D dominant model, showed univariate association with all three neurological deficit and severity parameters, EDSS, MSSS and gARMSS, in RRMS patients, we performed multiple linear regression analysis for EDSS, MSSS and gARMSS in RRMS patients with a model that included the following: sex, disease duration, age at MS onset, rs111833532 I/D according to allele D dominant model, and presence of the HLA-DRB1*15:01 rs3135388 risk A allele. Here, RAB4B is linked to myeloid sarcoma.