NPPB and hydrops fetalis: In a cohort of 341 patients with stable CHF, the cut-off levels for NT-proBNP for predicting cardiac events or hospitalization due to worsening HF were ≥ 1474 pg/mL for those with eGFR < 60 mL/min [17], similar to the cut-off found in our study sample for all-cause mortality in patients with the same GFR.