SLC5A2 and chronic kidney disease: However, a personalized approach may be considered in CKD management, as a one-size-fits-all strategy may not suit older adults with mild or slowly progressing CKD and different comorbidities (e.g., diabetes), and the data supporting a low-protein diet were primarily gathered before the wide spread use of renoprotective agents such as RAAS inhibitors and SGLT2 inhibitors.