TNC and cancer: The concentrations of TN-C in the subgroups of patients with different degrees of cancer invasiveness differed significantly compared to the control group K-W: H (2, N = 88) = 10.57; p = 0.005 However, no significant difference was found between the subgroups, although the mean TN-C concentration in MIBC was 1.2-fold higher than in NMIBC.