IL6 and radiodermatitis: Specifically, Elisa E. Córdoba et al. (2018) [15] reported that TNF-α (rs1800629) (OR = 5.83, p = 0.22) and IL-6 (rs1800795) (OR = 2.16, p = 0.54) were not significantly associated with an increased risk of severe radiodermatitis (grades 3 and 4).